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METTL3 Antibody - middle region : FITC (ARP39391_P050-FITC)

Selected Variant

ARP39391_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Methyltransferase like 3

Gene Aliases

M6A, IME4, Spo8, MT-A70, hMETTL3

Gene ID

56339

Swiss Prot

Q86U44

Accession Number

NP_062826

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human METTL3

Target

METTL3 is the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Partner Proteins

UBC; METTL14; UBD

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292

Shipping Conditions

Wet Ice

Protein Length

580

NCBI Gene Symbol

METTL3

NCBI GB Accession Number

METTL3

Host or Source

Rabbit

Protein Name

N6-adenosine-methyltransferase 70 kDa subunit

Nucleotide Accession Number

NM_019852

Peptide Sequence

IVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLD

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