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DCP1A Antibody - N-terminal region : HRP (ARP39353_T100-HRP)

Selected Variant

ARP39353_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

DCP1 decapping enzyme homolog A (S. cerevisiae)

Gene Aliases

SMIF, SMAD4IP1, HSA275986, Nbla00360

Gene ID

55802

Swiss Prot

Q9NPI6

Accession Number

NP_060873

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1A

Target

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Partner Proteins

RITA1; PNRC2; FHL2; MAPK3; DCP1B; DCP2; EDC3; EDC4; BAG4; DDX6; UBC; KANK2; PNRC1; AASS; TRIP13; EIF2B4; PFKM; XRN1; ZFP36; UPF1; SMAD4; HSPA1L; PAXIP1; MAPK8; USP4; AGO2; AGO1; LSM8; YWHAG; TTF2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

DCP1A is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Lehner, B. (2004) Genome Res. 14 (7), 1315-1323

Shipping Conditions

Wet Ice

Protein Length

515

NCBI Gene Symbol

DCP1A

NCBI GB Accession Number

DCP1A

Host or Source

Rabbit

Protein Name

MRNA-decapping enzyme 1A

Nucleotide Accession Number

NM_018403

Peptide Sequence

MEALSRAGQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQWEKTDI

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