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DCP1A Antibody - N-terminal region: FITC (ARP39353_T100-FITC)

Product Specifications

Gene Name

DCP1 decapping enzyme homolog A (S. cerevisiae)

Gene Aliases

SMIF, SMAD4IP1, HSA275986, Nbla00360

Gene ID

55802

Swiss Prot

Q9NPI6

Accession Number

NP_060873

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1A

Target

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.

Partner Proteins

RITA1; PNRC2; FHL2; MAPK3; DCP1B; DCP2; EDC3; EDC4; BAG4; DDX6; UBC; KANK2; PNRC1; AASS; TRIP13; EIF2B4; PFKM; XRN1; ZFP36; UPF1; SMAD4; HSPA1L; PAXIP1; MAPK8; USP4; AGO2; AGO1; LSM8; YWHAG; TTF2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Sample Type

DCP1A is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

Shipping Conditions

Wet Ice

Protein Length

515

NCBI Gene Symbol

DCP1A

Protein Name

MRNA-decapping enzyme 1A

Nucleotide Accession Number

NM_018403

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