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TRIM68 Antibody - middle region : Biotin (ARP39328_P050-Biotin)

Product Specifications

Gene Name

Tripartite motif containing 68

Gene Aliases

SS56, GC109, SS-56, RNF137

Gene ID

55128

Swiss Prot

Q6AZZ1

Accession Number

NP_060543

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRIM68

Target

The protein encoded by TRIM68 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. TRIM68 is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. TRIM68 was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells. The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.

Partner Proteins

NLRP1; TFG; VIM; UBC; HSP90B1; HNRNPL; BTN1A1; UBE2D3; UBE2U; KAT5; AR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 79%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Miyajima, N., (2008) Cancer Res. 68 (9), 3486-3494

Shipping Conditions

Wet Ice

Protein Length

485

NCBI Gene Symbol

TRIM68

NCBI GB Accession Number

TRIM68

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase TRIM68

Nucleotide Accession Number

NM_018073

Peptide Sequence

VIRLRKGNEYRAGTDEYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGS

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