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ERGIC2 Antibody - N-terminal region : HRP (ARP39265_T100-HRP)

Selected Variant

ARP39265_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

ERGIC and golgi 2

Gene Aliases

PTX1, CDA14, Erv41, cd002

Gene ID

51290

Swiss Prot

Q96RQ1

Accession Number

NP_057654

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERGIC2

Target

ERGIon Channel2 possibly play role in transport between endoplasmic reticulum and Golgi. ERGIon Channel2 is downregulated in prostate cancer. ERGIon Channel2 may play an important role in the growth and tumorigenicity of PC-3 prostate tumor cells. Ectopic expression of a partial sequence of ERGIon Channel2 as a VP22-fusion protein in prostate cancer cell line, PC-3, induced cellular senescence. Interferon-beta (IFN-beta) and a number of IFN-inducible genes were upregulated by the ERGIon Channel2-VP22 fusion protein.

Partner Proteins

Env; UBC; Copa

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 87%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

References & Citations

Breuza, L., (2004) J. Biol. Chem. 279 (45), 47242-47253

Shipping Conditions

Wet Ice

Protein Length

377

NCBI Gene Symbol

ERGIC2

NCBI GB Accession Number

ERGIC2

Host or Source

Rabbit

Protein Name

Endoplasmic reticulum-Golgi intermediate compartment protein 2

Nucleotide Accession Number

NM_016570

Peptide Sequence

MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIM

Price

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