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ADNP Antibody - N-terminal region : HRP (ARP39186_P050-HRP)

Selected Variant

ARP39186_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Activity-dependent neuroprotector homeobox

Gene Aliases

ADNP1, HVDAS, MRD28

Gene ID

23394

Swiss Prot

Q9H2P0

Accession Number

NP_056154

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ADNP

Target

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. It contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It is also upregulated in normal proliferative tissues. Finally, ADNP may increase the viability of certain cell types through modulation of p53 activity.Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

Partner Proteins

UBC; SUMO2; EED; RNF2; BMI1; HDAC1; HDAC11; MYC; CDC27; CBX5; PHGDH; RRS1; EBNA1BP2; SAP18; NFIA; SEPT2; EMD; SIRT7; CBX3; CBX1; MAP1LC3B; ARID1A; SMARCC2; SMARCA4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

124kDa

References & Citations

Mandel, S. (2007) J. Biol. Chem. 282 (47), 34448-34456

Shipping Conditions

Wet Ice

Protein Length

1102

NCBI Gene Symbol

ADNP

NCBI GB Accession Number

ADNP

Host or Source

Rabbit

Protein Name

Activity-dependent neuroprotector homeobox protein

Nucleotide Accession Number

NM_015339

Peptide Sequence

EDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKF

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