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JMJD6 Antibody - N-terminal region : Biotin (ARP39180_P050-Biotin)

Selected Variant

ARP39180_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Jumonji domain containing 6

Gene Aliases

PSR, PTDSR, PTDSR1

Gene ID

23210

Swiss Prot

Q6NYC1

Accession Number

NP_055982

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human JMJD6

Target

JMJD6 is a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor.This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

NAA50; FRMD6; UBC; C17orf97; RSPO2; STAC3; FAM9A; FGD5; AEBP2; CENPL; PRPF38A; ANKEF1; CCNL1; CAND1; ASUN; NHP2; SLFN12; VPS29; LARP7; ZCCHC17; RSRC1; CYHR1; RANBP6; ZNF451; BRD4; DIP2A; SWAP70; XPO7; SEC24A; SLU7; DNM1L; HMGXB4; GNA14; VPS26A; TAF1A; HIS

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Chang, B., (2007) Science 318 (5849), 444-447

Shipping Conditions

Wet Ice

Protein Length

403

NCBI Gene Symbol

JMJD6

NCBI GB Accession Number

JMJD6

Host or Source

Rabbit

Protein Name

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

Nucleotide Accession Number

NM_015167

Peptide Sequence

NHKSKKRIREAKRSARPELKDSLDWTRHNYYESFSLSPAAVADNVERADA

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