ARNT2 Antibody - N-terminal region : FITC (ARP39146_P050-FITC)

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

TRIM42; CEP57L1; RFX6; MIPOL1; DYDC1; SSX2IP; DTX2; SYCE1; RIMBP3; ZNF341; LZTS2; USHBP1; CEP63; CCDC33; NPAS3; RINT1; NDE1; ADAMTSL4; MTUS2; IKZF3; RBCK1; SPAG5; TACC3; CALCOCO2; SORBS3; PDE4DIP; TRAF4; BZRAP1; TFIP11; SSBP3; DGCR6; NCOA3; TRIP6; TRAF2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.