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ZEB2 Antibody - middle region : Biotin (ARP39141_P050-Biotin)

Product Specifications

Gene Name

Zinc finger E-box binding homeobox 2

Gene Aliases

SIP1, SIP-1, ZFHX1B, HSPC082, SMADIP1

Gene ID

9839

Swiss Prot

O60315

Accession Number

NP_055610

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ZEB2

Target

The ZFHX1B gene is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. ZFHX1B is strongly transcribed at an early stage in the developing peripheral and central nervous systems of both mice and humans, in all neuronal regions of the brains of 25-week human fetuses and adult mice, and in numerous nonneural tissues. The SMADIP1 gene (also known as SIP1) is a member of the delta-EF1 (ZEB1; MIM 189909) /Zfh1 family of 2-handed zinc finger/homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs (see MIM 605568) (Verschueren et al., 1999 [PubMed 10400677]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-58 AB056507.1 1-58 59-553 AL118674.1 57-551 554-5558 AB056507.1 553-5557 5559-5583 AI858477.1 1-25 c

Partner Proteins

CTBP1; SOX2; SMAD9; SMAD3; SMAD2; SMAD1; APP; HDAC4; CBX4; SUMO1; UBE2I; ELAVL1; UBC; MTA2; MTA1; RBBP7; RBBP4; HDAC2; HDAC1; CEBPA; COPS6; SMAD5; CTBP2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

136kDa

References & Citations

Verstappen, G., (2008) Hum. Mol. Genet. 17 (8), 1175-1183

Shipping Conditions

Wet Ice

Protein Length

1214

NCBI Gene Symbol

ZEB2

NCBI GB Accession Number

ZEB2

Host or Source

Rabbit

Protein Name

Zinc finger E-box-binding homeobox 2

Nucleotide Accession Number

NM_014795

Peptide Sequence

LGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKME

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