NFYC Antibody - C-terminal region : Biotin (ARP39066_P050-Biotin)

NFYC is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. NFYC forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Additional regulation, preliminarily supported by the EST database, may be represented by alternative splicing in this subunit.

NFYA; CDK2; UBC; SNX2; NFYB; Cebpb; ELAVL1; GAPDH; KAT2B; TP73; TAF12; TAF11; TAF6; TBPL2; TRIM27; HDAC1; KIAA2018; ARID2; GLTSCR1; GLTSCR1L; ZDHHC17; CIC; POGZ; ATF6; ADNP2; LMO4; SREBF2; SP1; DR1; CSN2; DST; SMAD3; SMAD2; ATF6B; MYC; TBP

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.