UHRF1 Antibody - N-terminal region : FITC (ARP39021_P050-FITC)
Product Specifications
Gene Name
Ubiquitin-like with PHD and ring finger domains 1
Gene Aliases
Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95
Gene ID
29128
Swiss Prot
Q2HIX7
Accession Number
NP_037414
Host
Rabbit
Reactivity
Human, Rat, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF1
Target
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2
Partner Proteins
UBC; H3F3B; H3F3A; HIST2H3D; HIST2H3A; HIST2H3C; UHRF1; HIST1H3F; HIST1H3B; HIST1H3E; HIST1H3C; HIST1H3D; HIST1H3A; HIST3H3; DNMT1; PARP1; PARP2; RNF2; USP7; KAT5; MPG; BTRC; CUL1; ZPR1; RB1; PRKACA; PML; SUV39H1; EZH2; SUZ12; UHRF2; USP11; HDAC1; ELAVL1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 79%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rat: 86%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
91kDa
References & Citations
Achour, M., (2008) Oncogene 27 (15), 2187-2197
Shipping Conditions
Wet Ice
Protein Length
806
NCBI Gene Symbol
UHRF1
NCBI GB Accession Number
UHRF1
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase UHRF1
Nucleotide Accession Number
NM_013282
Peptide Sequence
MGVFAVPPLSADTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFH
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