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UHRF1 Antibody - N-terminal region : Biotin (ARP39021_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin-like with PHD and ring finger domains 1

Gene Aliases

Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95

Gene ID

29128

Swiss Prot

Q2HIX7

Accession Number

NP_037414

Host

Rabbit

Reactivity

Human, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF1

Target

This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2

Partner Proteins

UBC; H3F3B; H3F3A; HIST2H3D; HIST2H3A; HIST2H3C; UHRF1; HIST1H3F; HIST1H3B; HIST1H3E; HIST1H3C; HIST1H3D; HIST1H3A; HIST3H3; DNMT1; PARP1; PARP2; RNF2; USP7; KAT5; MPG; BTRC; CUL1; ZPR1; RB1; PRKACA; PML; SUV39H1; EZH2; SUZ12; UHRF2; USP11; HDAC1; ELAVL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rat: 86%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

References & Citations

Achour, M., (2008) Oncogene 27 (15), 2187-2197

Shipping Conditions

Wet Ice

Protein Length

806

NCBI Gene Symbol

UHRF1

NCBI GB Accession Number

UHRF1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase UHRF1

Nucleotide Accession Number

NM_013282

Peptide Sequence

MGVFAVPPLSADTMWIQVRTMDGRQTHTVDSLSRLTKVEELRRKIQELFH

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