BRD7 Antibody - C-terminal region : HRP (ARP39018_P050-HRP)
Product Specifications
Gene Name
Bromodomain containing 7
Gene Aliases
BP75, NAG4, CELTIX1
Gene ID
29117
Swiss Prot
Q9NPI1
Accession Number
NP_037395
Host
Rabbit
Reactivity
Human, Rat, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7
Target
BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.
Partner Proteins
UBC; Dvl1; HIST2H3C; BRD2; NEFL; BARD1; LRIF1; HAP1; TFAP4; TRIM24; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; CHD7; ARID2; RBFOX2; BCL7C; SMARCC1; SMARCA4; PCBD1; POU2F1; MYC; BRCA1; BHLHE40; HIST2H4A; HIST2H3A; BTBD2; RIF1; HNRNPUL1; HIST1H2AL; AGR2; PSMD
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 86%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
74kDa
References & Citations
Zhou, J., (2004) J. Cell. Physiol. 200 (1), 89-98
Shipping Conditions
Wet Ice
Protein Length
651
NCBI Gene Symbol
BRD7
NCBI GB Accession Number
BRD7
Host or Source
Rabbit
Protein Name
Bromodomain-containing protein 7
Nucleotide Accession Number
NM_013263
Peptide Sequence
KELAQQVTPGDIVSTYGVRKAMGISIPSPVMENNFVDLTEDTEEPKKTDV
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