BRD7 Antibody - C-terminal region : FITC (ARP39018_P050-FITC)

Product Specifications

Gene Name

Bromodomain containing 7

Gene Aliases

BP75, NAG4, CELTIX1

Gene ID

29117

Swiss Prot

Q9NPI1

Accession Number

NP_037395

Host

Rabbit

Reactivity

Human, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7

Target

BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.

Partner Proteins

UBC; Dvl1; HIST2H3C; BRD2; NEFL; BARD1; LRIF1; HAP1; TFAP4; TRIM24; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; CHD7; ARID2; RBFOX2; BCL7C; SMARCC1; SMARCA4; PCBD1; POU2F1; MYC; BRCA1; BHLHE40; HIST2H4A; HIST2H3A; BTBD2; RIF1; HNRNPUL1; HIST1H2AL; AGR2; PSMD

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.