BRD7 Antibody - C-terminal region : Biotin (ARP39018_P050-Biotin)

Product Specifications

Gene Name

Bromodomain containing 7

Gene Aliases

BP75, NAG4, CELTIX1

Gene ID

29117

Swiss Prot

Q9NPI1

Accession Number

NP_037395

Host

Rabbit

Reactivity

Human, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7

Target

BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.

Partner Proteins

UBC; Dvl1; HIST2H3C; BRD2; NEFL; BARD1; LRIF1; HAP1; TFAP4; TRIM24; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; CHD7; ARID2; RBFOX2; BCL7C; SMARCC1; SMARCA4; PCBD1; POU2F1; MYC; BRCA1; BHLHE40; HIST2H4A; HIST2H3A; BTBD2; RIF1; HNRNPUL1; HIST1H2AL; AGR2; PSMD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Dog: 86%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.