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LDOC1 Antibody - N-terminal region : FITC (ARP38983_P050-FITC)

Product Specifications

Gene Name

Leucine zipper, down-regulated in cancer 1

Gene Aliases

Mar7, RTL7, BCUR1, Mart7, SIRH7

Gene ID

23641

Swiss Prot

O95751

Accession Number

NP_036449

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

Target

LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB) . The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Partner Proteins

LENG1; TTC23; MEAF6; SH2D4A; CTNNBL1; DPPA4; FAM90A1; C1orf109; FAM208B; TBC1D7; PRPF31; LDOC1; PEG10; NXF1; ZBTB24; HDAC4; ATP6V1G1; HGS; LATS1; RAB29; TNNT1; TMSB4XP1; SDCBP; DPF2; PSMA1; MFAP1; BARD1; ATF4; AES; ZNF774; ZNF564; HAUS1; ZGPAT; CCDC33; IN

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Rabbit: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

17kDa

References & Citations

Ross, M.T., (2005) Nature 434 (7031), 325-337

Shipping Conditions

Wet Ice

Protein Length

146

NCBI Gene Symbol

LDOC1

NCBI GB Accession Number

LDOC1

Host or Source

Rabbit

Protein Name

Protein LDOC1

Nucleotide Accession Number

NM_012317

Peptide Sequence

MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCP

Frequently Asked Questions

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