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BRD3 Antibody - N-terminal region : Biotin (ARP38939_T100-Biotin)

Product Specifications

Gene Name

Bromodomain containing 3

Gene Aliases

ORFX, RING3L

Gene ID

8019

Swiss Prot

Q5T1R6

Accession Number

AAH32124

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BRD3

Target

This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. BRD3 is ubiquitously expressed in human adult and fetal tissues. BRD3 is markedly expressed in undifferentiated ES cells, whereas the expression was reduced upon endothelial differentiation. BRD3 plays a role in regulation of cell proliferation by allowing cells to enter the proliferative phase of the angiogenic process.BRD3 is also involved in bladder cancer.

Partner Proteins

SRPK2; MYC; UBC; YEATS4; APP; SPP1; ELAVL1; MAP1LC3B; tat; BRD7

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

BRD3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Ishii, H., (2005) DNA Cell Biol. 24 (7), 432-437

Shipping Conditions

Wet Ice

Product Datasheet

Anti-BRD3 (ARP38939_T100-Biotin) antibody

Protein Length

556

NCBI Gene Symbol

BRD3

NCBI GB Accession Number

BRD3

Host or Source

Rabbit

Nucleotide Accession Number

NM_007371

Peptide Sequence

MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTL

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