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NR1H2 Antibody - N-terminal region : Biotin (ARP38906_T100-Biotin)

Product Specifications

Gene Name

Nuclear receptor subfamily 1, group H, member 2

Gene Aliases

NER, UNR, LXRB, LXR-b, NER-I, RIP15

Gene ID

7376

Swiss Prot

Q68CY8

Accession Number

NP_009052

Host

Rabbit

Reactivity

Human, Rat, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H2

Target

The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995) .[supplied by OMIM].

Partner Proteins

RXRG; MDFI; KDM1A; SUV39H1; ACVRL1; LAMC3; NCOR2; YY1; NPY; CDKN1A; PPARGC1B; PDCD4; PIAS1; USP7; PRKCA; SENP3; CORO2A; MPP1; COL4A5; CHD3; RMI1; CSAD; DUSP12; C14orf1; FAF1; SPRY2; HMGXB4; SORBS2; BAG6; VIM; UBE2D1; SMPD1; ROBO2; NCOR1; NRIP1; NCOA3; VDR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Dog: 90%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Albers, M., (2006) J. Biol. Chem. 281 (8), 4920-4930

Shipping Conditions

Wet Ice

Protein Length

460

Applications Notes

ChIP

NCBI Gene Symbol

NR1H2

NCBI GB Accession Number

NR1H2

Host or Source

Rabbit

Protein Name

Putative uncharacterized protein DKFZp686D1580 EMBL CAH18442.1

Nucleotide Accession Number

NM_007121

Peptide Sequence

GNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPD

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