NR1H2 Antibody - N-terminal region : Biotin (ARP38906_T100-Biotin)
Product Specifications
Gene Name
Nuclear receptor subfamily 1, group H, member 2
Gene Aliases
NER, UNR, LXRB, LXR-b, NER-I, RIP15
Gene ID
7376
Swiss Prot
Q68CY8
Accession Number
NP_009052
Host
Rabbit
Reactivity
Human, Rat, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H2
Target
The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995) .[supplied by OMIM].
Partner Proteins
RXRG; MDFI; KDM1A; SUV39H1; ACVRL1; LAMC3; NCOR2; YY1; NPY; CDKN1A; PPARGC1B; PDCD4; PIAS1; USP7; PRKCA; SENP3; CORO2A; MPP1; COL4A5; CHD3; RMI1; CSAD; DUSP12; C14orf1; FAF1; SPRY2; HMGXB4; SORBS2; BAG6; VIM; UBE2D1; SMPD1; ROBO2; NCOR1; NRIP1; NCOA3; VDR
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Dog: 90%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Albers, M., (2006) J. Biol. Chem. 281 (8), 4920-4930
Shipping Conditions
Wet Ice
Protein Length
460
Applications Notes
ChIP
NCBI Gene Symbol
NR1H2
NCBI GB Accession Number
NR1H2
Host or Source
Rabbit
Protein Name
Putative uncharacterized protein DKFZp686D1580 EMBL CAH18442.1
Nucleotide Accession Number
NM_007121
Peptide Sequence
GNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPD
Frequently Asked Questions
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