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CORO1A Antibody - N-terminal region : FITC (ARP38899_T100-FITC)

Selected Variant

ARP38899_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Coronin, actin binding protein, 1A

Gene Aliases

P57, IMD8, TACO, CLABP, HCORO1, CLIPINA

Gene ID

11151

Swiss Prot

Q2YD73

Accession Number

NP_009005

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CORO1A

Target

CORO1A is a novel actin-binding protein with a WD repeat and a leucine zipper motif. CORO1A forms homodimers, that the association is mediated by the leucine zipper structure in the C-terminal region, and that it plays a role in the cross-linking of F-actin in the cell. The leukocyte plasma membrane associates with the actin cytoskeleton through CORO1A.Downregulation of CORO1A gene transcription restricts entry/survival of mycobacteria within macrophages

Partner Proteins

FSD2; GOLGA2; UBC; YTHDC1; SPATA20; POT1; TAB1; GIT2; POLR1C; STAT3; SMARCD1; MAGOH; SMAD3; LMO2; FHL3; FMNL1; NCF4; THBS1; ACTB; DKK1; UBE2G2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Sample Type

CORO1A is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Anand, P.K. (2005) FEMS Microbiol. Lett. 250 (1), 137-144

Shipping Conditions

Wet Ice

Protein Length

461

NCBI Gene Symbol

CORO1A

NCBI GB Accession Number

CORO1A

Host or Source

Rabbit

Protein Name

Coronin-1A

Nucleotide Accession Number

NM_007074

Peptide Sequence

MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALI

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