ZNF197 Antibody - middle region : Biotin (ARP38894_P050-Biotin)
Product Specifications
Gene Name
Zinc finger protein 197
Gene Aliases
P18, VHLaK, ZNF20, ZNF166, ZKSCAN9, ZSCAN41, D3S1363E
Gene ID
10168
Swiss Prot
O14709
Accession Number
NP_008922
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ZNF197
Target
ZNF197 belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.
Partner Proteins
UBC; NDEL1; DISC1; ZNF197; TRIM28; VHL; HIF1A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 83%; Horse: 85%; Human: 100%; Pig: 79%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
119kDa
References & Citations
Li, Z., (2003) EMBO J. 22 (8), 1857-1867
Shipping Conditions
Wet Ice
Protein Length
1029
NCBI Gene Symbol
ZNF197
NCBI GB Accession Number
ZNF197
Host or Source
Rabbit
Protein Name
Zinc finger protein 197
Nucleotide Accession Number
NM_006991
Peptide Sequence
NLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHTIEEFSWLQNTNE
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