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ZNF197 Antibody - middle region : Biotin (ARP38894_P050-Biotin)

Product Specifications

Gene Name

Zinc finger protein 197

Gene Aliases

P18, VHLaK, ZNF20, ZNF166, ZKSCAN9, ZSCAN41, D3S1363E

Gene ID

10168

Swiss Prot

O14709

Accession Number

NP_008922

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ZNF197

Target

ZNF197 belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.

Partner Proteins

UBC; NDEL1; DISC1; ZNF197; TRIM28; VHL; HIF1A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 83%; Horse: 85%; Human: 100%; Pig: 79%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

119kDa

References & Citations

Li, Z., (2003) EMBO J. 22 (8), 1857-1867

Shipping Conditions

Wet Ice

Protein Length

1029

NCBI Gene Symbol

ZNF197

NCBI GB Accession Number

ZNF197

Host or Source

Rabbit

Protein Name

Zinc finger protein 197

Nucleotide Accession Number

NM_006991

Peptide Sequence

NLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHTIEEFSWLQNTNE

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