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RORB Antibody - C-terminal region : Biotin (ARP38879_P050-Biotin)

Product Specifications

Gene Name

RAR-related orphan receptor B

Gene Aliases

RZRB, EIG15, NR1F2, ROR-BETA, RZR-BETA, bA133M9.1

Gene ID

6096

Swiss Prot

Q98934

Accession Number

NP_008845

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RORB

Target

RORB is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

NSD1; NCOA1; NCOA6; PNRC1; EIF3I; NRIP1; UBE2I; TNNI2; SRC; PSMC4; NPPA; MAP6; PNRC2; NRIP2; NME2; NME1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Humphray, S.J., (2004) Nature 429 (6990), 369-374

Shipping Conditions

Wet Ice

Protein Length

459

NCBI Gene Symbol

RORB

NCBI GB Accession Number

RORB

Host or Source

Rabbit

Protein Name

Nuclear orphan receptor ROR-beta EMBL CAA69928.1

Nucleotide Accession Number

NM_006914

Peptide Sequence

KNHLDDETLAKLIAKIPTITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYK

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