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LZTR1 Antibody - N-terminal region : HRP (ARP38862_P050-HRP)

Selected Variant

ARP38862_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Leucine-zipper-like transcription regulator 1

Gene Aliases

NS2, NS10, BTBD29, LZTR-1, SWNTS2

Gene ID

8216

Swiss Prot

Q8N653

Accession Number

NP_006758

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human LZTR1

Target

Leucine-zipper-like transcriptional regulator 1 (LZTR1) is belived to be a DNA-binding protein and transcriptional regulator based on its predicted structural characteristics. The transcript is present in several essential fetal organs and is hemizygously deleted in some DiGeorge syndrome patients. LZTR1 is thought to play a critical role in embryogenesis.This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome.

Partner Proteins

LZTR1; TUBGCP4; CUL3; UBC; CNOT6L; ZNF584; ZNF714; ASB12; FANK1; TRIM5; KDM2B; L3MBTL3; POLR1B; ANKRD53; EHMT1; E2F8; PAPOLG; ZNF490; SND1; AATF; ZNF451; ZZZ3; SCMH1; ZBTB1; WWP1; RAI1; CEBPZ; SUGP2; NR1H3; CHAF1A; MED16; HDAC4; MED7; RUVBL1; IKBKG; ZNF17

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

References & Citations

Nacak, T.G., (2006) J. Biol. Chem. 281 (8), 5065-5071

Shipping Conditions

Wet Ice

Protein Length

840

NCBI Gene Symbol

LZTR1

NCBI GB Accession Number

LZTR1

Host or Source

Rabbit

Protein Name

Leucine-zipper-like transcriptional regulator 1

Nucleotide Accession Number

NM_006767

Peptide Sequence

AGPGSTGGQIGAAALAGGARSKVAPSVDFDHSCSDSVEYLTLNFGPFETV

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