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TCERG1 Antibody - N-terminal region : FITC (ARP38850_P050-FITC)

Selected Variant

ARP38850_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Transcription elongation regulator 1

Gene Aliases

Urn1, CA150, TAF2S

Gene ID

10915

Swiss Prot

O14776

Accession Number

NP_006697

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TCERG1

Target

TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Partner Proteins

CEP76; UBC; RPA3; RPA2; RPA1; EED; WIPF2; PSPC1; WWOX; EVL; CYFIP2; BRD4; SF3B1; SF3B3; CYFIP1; U2AF2; WBP4; CPSF6; NUDT21; SF3B2; SF3A3; DIAPH2; DIAPH1; FMNL1; SF3A1; WASF2; ABI1; SF3A2; SF1; WAS; SFPQ; NONO; HNRNPU; HNRNPK; JUNB; FN1; Dlg4; ITGA4; PSAP

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TCERG1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

124kDa

References & Citations

Pearson, J.L., (2008) J. Biol. Chem. 283 (12), 7949-7961

Shipping Conditions

Wet Ice

Protein Length

1098

NCBI Gene Symbol

TCERG1

NCBI GB Accession Number

TCERG1

Host or Source

Rabbit

Protein Name

Transcription elongation regulator 1

Nucleotide Accession Number

NM_006706

Peptide Sequence

AERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPP

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