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TCERG1 Antibody - N-terminal region : Biotin (ARP38850_P050-Biotin)

Selected Variant

ARP38850_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Transcription elongation regulator 1

Gene Aliases

Urn1, CA150, TAF2S

Gene ID

10915

Swiss Prot

O14776

Accession Number

NP_006697

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TCERG1

Target

TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Partner Proteins

CEP76; UBC; RPA3; RPA2; RPA1; EED; WIPF2; PSPC1; WWOX; EVL; CYFIP2; BRD4; SF3B1; SF3B3; CYFIP1; U2AF2; WBP4; CPSF6; NUDT21; SF3B2; SF3A3; DIAPH2; DIAPH1; FMNL1; SF3A1; WASF2; ABI1; SF3A2; SF1; WAS; SFPQ; NONO; HNRNPU; HNRNPK; JUNB; FN1; Dlg4; ITGA4; PSAP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TCERG1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

124kDa

References & Citations

Pearson, J.L., (2008) J. Biol. Chem. 283 (12), 7949-7961

Shipping Conditions

Wet Ice

Protein Length

1098

NCBI Gene Symbol

TCERG1

NCBI GB Accession Number

TCERG1

Host or Source

Rabbit

Protein Name

Transcription elongation regulator 1

Nucleotide Accession Number

NM_006706

Peptide Sequence

AERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPP

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