TFEB Antibody - C-terminal region: FITC (ARP38810_T100-FITC)
Product Specifications
Gene Name
Transcription factor EB
Gene Aliases
TCFEB, BHLHE35, ALPHATFEB
Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_009093
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TFEB
Target
TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t (6;11) (p21; q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Partner Proteins
SRPK1; YWHAQ; TFEC; TFE3; MITF
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 85%; Yeast: 100%; Zebrafish: 91%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
53kDa
Shipping Conditions
Wet Ice
Protein Length
476
NCBI Gene Symbol
TFEB
Protein Name
Transcription factor EB
Nucleotide Accession Number
NM_007162
Curated Selection
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