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HIC1 Antibody - middle region : HRP (ARP38806_P050-HRP)

Product Specifications

Gene Name

Hypermethylated in cancer 1

Gene Aliases

Hic-1, ZBTB29, ZNF901

Gene ID

3090

Swiss Prot

Q14526

Accession Number

NP_006488

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HIC1

Target

HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

Partner Proteins

PIAS4; PIAS3; PIAS2; SP1; STAT3; SIRT1; MTA1; UBE2I; SUMO2; HIC2; TCF4; CTBP2; CTBP1; EED; PHF1; EZH2; PHF19; SUZ12; UBC; MBD3; RBBP4; CHD3; SENP3; HDAC4; PIAS1; ARID1A; HIC1; HDAC1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HIC1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Stocklein, H., (2008) Oncogene 27 (18), 2613-2625

Shipping Conditions

Wet Ice

Protein Length

714

NCBI Gene Symbol

HIC1

NCBI GB Accession Number

HIC1

Host or Source

Rabbit

Protein Name

Hypermethylated in cancer 1 protein

Nucleotide Accession Number

NM_006497

Peptide Sequence

GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGE

Frequently Asked Questions

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