HIC1 Antibody - middle region : FITC (ARP38806_P050-FITC)
Product Specifications
Gene Name
Hypermethylated in cancer 1
Gene Aliases
Hic-1, ZBTB29, ZNF901
Gene ID
3090
Swiss Prot
Q14526
Accession Number
NP_006488
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HIC1
Target
HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.
Partner Proteins
PIAS4; PIAS3; PIAS2; SP1; STAT3; SIRT1; MTA1; UBE2I; SUMO2; HIC2; TCF4; CTBP2; CTBP1; EED; PHF1; EZH2; PHF19; SUZ12; UBC; MBD3; RBBP4; CHD3; SENP3; HDAC4; PIAS1; ARID1A; HIC1; HDAC1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
HIC1 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
74kDa
References & Citations
Stocklein, H., (2008) Oncogene 27 (18), 2613-2625
Shipping Conditions
Wet Ice
Protein Length
714
NCBI Gene Symbol
HIC1
NCBI GB Accession Number
HIC1
Host or Source
Rabbit
Protein Name
Hypermethylated in cancer 1 protein
Nucleotide Accession Number
NM_006497
Peptide Sequence
GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGE
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