HIC1 Antibody - middle region : Biotin (ARP38806_P050-Biotin)

Product Specifications

Gene Name

Hypermethylated in cancer 1

Gene Aliases

Hic-1, ZBTB29, ZNF901

Gene ID

3090

Swiss Prot

Q14526

Accession Number

NP_006488

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HIC1

Target

HIC1 is a transcriptional repressor. HIC1 may act as a tumor suppressor. HIC1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIC1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

Partner Proteins

PIAS4; PIAS3; PIAS2; SP1; STAT3; SIRT1; MTA1; UBE2I; SUMO2; HIC2; TCF4; CTBP2; CTBP1; EED; PHF1; EZH2; PHF19; SUZ12; UBC; MBD3; RBBP4; CHD3; SENP3; HDAC4; PIAS1; ARID1A; HIC1; HDAC1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

HIC1 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.