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PDLIM5 Antibody - N-terminal region : HRP (ARP38795_P050-HRP)

Selected Variant

ARP38795_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

PDZ and LIM domain 5

Gene Aliases

L9, ENH, LIM, ENH1

Gene ID

10611

Swiss Prot

Q96HC4

Accession Number

NP_006448

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PDLIM5

Target

PDLIM5 is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized. The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.

Partner Proteins

KRTAP10-7; KRT40; CCDC136; COIL; ZYX; UBC; SUMO2; SUMO3; SUZ12; RNF2; BMI1; PDE12; NPLOC4; IPO11; PLIN3; UBA2; EIF4A3; ANP32A; TPD52; SRP14; RAD23B; PKM; METTL1; CBS; CALU; FN1; ELMSAN1; SIN3A; DSTN; NDUFA7; GFI1B; SUMO1; TRIM39; CACNA1B; PRKCG; PRKCE; PR

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that PDLIM5 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

References & Citations

Squassina, A., (2008) Psychiatr. Genet. 18 (3), 128-132

Shipping Conditions

Wet Ice

Protein Length

596

NCBI Gene Symbol

PDLIM5

NCBI GB Accession Number

PDLIM5

Host or Source

Rabbit

Protein Name

PDZ and LIM domain protein 5

Nucleotide Accession Number

NM_006457

Peptide Sequence

SNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVL

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