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POLR2I Antibody - N-terminal region : HRP (ARP38758_P050-HRP)

Selected Variant

ARP38758_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

Gene Aliases

RPB9, hRPB14.5

Gene ID

5438

Swiss Prot

P36954

Accession Number

NP_006224

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2I

Target

POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ESR1; TCEB3; SRC; PSMB9; UBC; MED19; MED26; RECQL5; TBCD; BRCA1; CPSF6; POLR2E; POLR2D; POLR2C; POLR2B; POLR2A; DCUN1D1; CUL5; MYC; tat; WDR48; POLR2H; MED10; MED29

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 83%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Grimwood, J., (2004) Nature 428 (6982), 529-535

Shipping Conditions

Wet Ice

Protein Length

125

NCBI Gene Symbol

POLR2I

NCBI GB Accession Number

POLR2I

Host or Source

Rabbit

Protein Name

DNA-directed RNA polymerase II subunit RPB9

Nucleotide Accession Number

NM_006233

Peptide Sequence

EPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNS

Subunit

RPB9

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