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PEG3 Antibody - C-terminal region : HRP (ARP38756_P050-HRP)

Product Specifications

Gene Name

Paternally expressed 3

Gene Aliases

PW1, ZNF904, ZSCAN24, ZKSCAN22

Gene ID

5178

Swiss Prot

Q9GZU2

Accession Number

NP_006201

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

Target

PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.

Partner Proteins

PEG3; ALB; USP7; TRAF2; SIAH2; SIAH1; BRCA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PEG3 is strongly supported by BioGPS gene expression data to be expressed in A204

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

181kDa

References & Citations

Dowdy, S.C., et al., (2005) Gynecol. Oncol. 99 (1), 126-134

Shipping Conditions

Wet Ice

Protein Length

1588

NCBI Gene Symbol

PEG3

NCBI GB Accession Number

PEG3

Host or Source

Rabbit

Protein Name

Paternally-expressed gene 3 protein

Nucleotide Accession Number

NM_006210

Peptide Sequence

FGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG

Frequently Asked Questions

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