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PEG3 Antibody - C-terminal region : Biotin (ARP38756_P050-Biotin)

Product Specifications

Gene Name

Paternally expressed 3

Gene Aliases

PW1, ZNF904, ZSCAN24, ZKSCAN22

Gene ID

5178

Swiss Prot

Q9GZU2

Accession Number

NP_006201

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

Target

PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.

Partner Proteins

PEG3; ALB; USP7; TRAF2; SIAH2; SIAH1; BRCA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PEG3 is strongly supported by BioGPS gene expression data to be expressed in A204

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

181kDa

References & Citations

Dowdy, S.C., et al., (2005) Gynecol. Oncol. 99 (1), 126-134

Shipping Conditions

Wet Ice

Protein Length

1588

NCBI Gene Symbol

PEG3

NCBI GB Accession Number

PEG3

Host or Source

Rabbit

Protein Name

Paternally-expressed gene 3 protein

Nucleotide Accession Number

NM_006210

Peptide Sequence

FGECSGYIERASTSTGGANQADEKYFKCDVCGQLFNDRLSLARHQNTHTG

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