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NKX3-1 Antibody - middle region : FITC (ARP38751_P050-FITC)

Product Specifications

Gene Name

NK3 homeobox 1

Gene Aliases

NKX3, BAPX2, NKX3A, NKX3.1

Gene ID

4824

Swiss Prot

Q99801

Accession Number

NP_006158

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NKX3-1

Target

The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.The homeodomain-containing transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

STRA13; CHPF; AEN; RABL6; TEX264; STMN3; LMCD1; SPDEF; CKAP4; HNRNPA0; CCT7; HMG20B; FEM1B; HSP90B1; TPT1; RPL37A; RARG; PTMS; PEBP1; ND4; MNAT1; MAN2B1; RPSA; TOP1; WDR77; TOPORS; KAT2B; SP5; SP4; SP3; SP2; SP1; HDAC1; HIPK2; SRF

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that NKX3-1 is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

26kDa

References & Citations

Possner, M., (2008) Int. J. Oncol. 32 (4), 877-884

Shipping Conditions

Wet Ice

Product Datasheet

Anti-NKX3-1 (ARP38751_P050-FITC) antibody

Protein Length

234

NCBI Gene Symbol

NKX3-1

NCBI GB Accession Number

NKX3-1

Host or Source

Rabbit

Protein Name

Homeobox protein Nkx-3.1

Nucleotide Accession Number

NM_006167

Peptide Sequence

FSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLE

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