NFE2L2 Antibody - C-terminal region : FITC (ARP38745_T100-FITC)

Product Specifications

Gene Name

Nuclear factor (erythroid-derived 2) -like 2

Gene Aliases

NRF2, HEBP1, Nrf-2, IMDDHH

Gene ID

4780

Swiss Prot

Q16236

Accession Number

NP_006155

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NFE2L2

Target

NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995) .[supplied by OMIM].

Partner Proteins

BACH1; HDAC3; WAC; FBXW11; KEAP1; TNNT1; MAPK7; HDAC2; HDAC1; MAFF; MAFG; MAFK; MAP2K2; MAP2K1; MAPK9; MAPK8; AKT1; UBC; NQO1; BRCA1; AHR; CREB3; NFE2L3; ENC1; SIAH2; NFE2; ATF4; Pparg; SUMO1; SUMO2; RNF4; BPTF; RBMX; KPNA3; SUMO3; MYC; DYT10; Ube2e1; PGA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

Sample Type

NFE2L2 is supported by BioGPS gene expression data to be expressed in A172

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.