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NFE2L2 Antibody : HRP (ARP38744_P050-HRP)

Selected Variant

ARP38744_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Nuclear factor (erythroid-derived 2) -like 2

Gene Aliases

NRF2, HEBP1, Nrf-2, IMDDHH

Gene ID

4780

Swiss Prot

Q16236

Accession Number

NP_006155

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence DIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL

Target

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

BACH1; HDAC3; WAC; FBXW11; KEAP1; TNNT1; MAPK7; HDAC2; HDAC1; MAFF; MAFG; MAFK; MAP2K2; MAP2K1; MAPK9; MAPK8; AKT1; UBC; NQO1; BRCA1; AHR; CREB3; NFE2L3; ENC1; SIAH2; NFE2; ATF4; Pparg; SUMO1; SUMO2; RNF4; BPTF; RBMX; KPNA3; SUMO3; MYC; DYT10; Ube2e1; PGA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 92%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68 kDa

Shipping Conditions

Wet Ice

Protein Length

605

NCBI Gene Symbol

NFE2L2

NCBI GB Accession Number

NFE2L2

Host or Source

Rabbit

Protein Name

Nuclear factor erythroid 2-related factor 2

Nucleotide Accession Number

NM_001145412

Peptide Sequence

DIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL

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