NFE2L2 Antibody : Biotin (ARP38744_P050-Biotin)
Product Specifications
Gene Name
Nuclear factor (erythroid-derived 2) -like 2
Gene Aliases
NRF2, HEBP1, Nrf-2, IMDDHH
Gene ID
4780
Swiss Prot
Q16236
Accession Number
NP_006155
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence DIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL
Target
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
BACH1; HDAC3; WAC; FBXW11; KEAP1; TNNT1; MAPK7; HDAC2; HDAC1; MAFF; MAFG; MAFK; MAP2K2; MAP2K1; MAPK9; MAPK8; AKT1; UBC; NQO1; BRCA1; AHR; CREB3; NFE2L3; ENC1; SIAH2; NFE2; ATF4; Pparg; SUMO1; SUMO2; RNF4; BPTF; RBMX; KPNA3; SUMO3; MYC; DYT10; Ube2e1; PGA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 92%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68 kDa
Shipping Conditions
Wet Ice
Protein Length
605
NCBI Gene Symbol
NFE2L2
NCBI GB Accession Number
NFE2L2
Host or Source
Rabbit
Protein Name
Nuclear factor erythroid 2-related factor 2
Nucleotide Accession Number
NM_001145412
Peptide Sequence
DIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL
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