TRIM22 Antibody - middle region : Biotin (ARP38734_P050-Biotin)
Product Specifications
Gene Name
Tripartite motif containing 22
Gene Aliases
RNF94, STAF50, GPSTAF50
Gene ID
10346
Swiss Prot
Q8IYM9
Accession Number
NP_006065
Host
Rabbit
Reactivity
Human, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TRIM22
Target
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
EIF4E; UBC; TAB2; CASK; CIC; TRIM22; USP7; RERE; ZZZ3; TAF7; CREB1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%; Pig: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
References & Citations
Obad, S., (2007) J. Interferon Cytokine Res. 27 (10), 857-864
Shipping Conditions
Wet Ice
Protein Length
498
NCBI Gene Symbol
TRIM22
NCBI GB Accession Number
TRIM22
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase TRIM22
Nucleotide Accession Number
NM_006074
Peptide Sequence
VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYW
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