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TRIM22 Antibody - middle region : Biotin (ARP38734_P050-Biotin)

Product Specifications

Gene Name

Tripartite motif containing 22

Gene Aliases

RNF94, STAF50, GPSTAF50

Gene ID

10346

Swiss Prot

Q8IYM9

Accession Number

NP_006065

Host

Rabbit

Reactivity

Human, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRIM22

Target

TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

EIF4E; UBC; TAB2; CASK; CIC; TRIM22; USP7; RERE; ZZZ3; TAF7; CREB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Pig: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Obad, S., (2007) J. Interferon Cytokine Res. 27 (10), 857-864

Shipping Conditions

Wet Ice

Protein Length

498

NCBI Gene Symbol

TRIM22

NCBI GB Accession Number

TRIM22

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase TRIM22

Nucleotide Accession Number

NM_006074

Peptide Sequence

VDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYW

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