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NAB2 Antibody - C-terminal region : Biotin (ARP38716_P050-Biotin)

Product Specifications

Gene Name

NGFI-A binding protein 2 (EGR1 binding protein 2)

Gene Aliases

MADER

Gene ID

4665

Swiss Prot

Q15742

Accession Number

NP_005958

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human NAB2

Target

NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

AES; KRT40; ZMYND19; TGIF2LY; TCHP; CCDC33; GCC1; LENG1; SCNM1; ZBED8; TTC19; CCHCR1; NME7; RBPMS; MORF4L1; JAKMIP2; RFC5; PIN1; PHF1; NEDD9; NAB2; MDFI; MCM7; PHOSPHO2; SUMO1P1; NOTCH2NL; KRTAP10-3; KRTAP10-8; TCEANC; CWF19L2; DGCR6; MAPK3; VBP1; TLN1; S

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

525

NCBI Gene Symbol

NAB2

NCBI GB Accession Number

NAB2

Host or Source

Rabbit

Protein Name

NGFI-A-binding protein 2

Nucleotide Accession Number

NM_005967

Peptide Sequence

GRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ

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