NAB2 Antibody - C-terminal region : Biotin (ARP38716_P050-Biotin)
Product Specifications
Gene Name
NGFI-A binding protein 2 (EGR1 binding protein 2)
Gene Aliases
MADER
Gene ID
4665
Swiss Prot
Q15742
Accession Number
NP_005958
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NAB2
Target
NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize withThis gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
AES; KRT40; ZMYND19; TGIF2LY; TCHP; CCDC33; GCC1; LENG1; SCNM1; ZBED8; TTC19; CCHCR1; NME7; RBPMS; MORF4L1; JAKMIP2; RFC5; PIN1; PHF1; NEDD9; NAB2; MDFI; MCM7; PHOSPHO2; SUMO1P1; NOTCH2NL; KRTAP10-3; KRTAP10-8; TCEANC; CWF19L2; DGCR6; MAPK3; VBP1; TLN1; S
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
References & Citations
Olsen, J.V., (2006) Cell 127 (3), 635-648
Shipping Conditions
Wet Ice
Protein Length
525
NCBI Gene Symbol
NAB2
NCBI GB Accession Number
NAB2
Host or Source
Rabbit
Protein Name
NGFI-A-binding protein 2
Nucleotide Accession Number
NM_005967
Peptide Sequence
GRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
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