Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

RBM5 Antibody - N-terminal region : Biotin (ARP38684_P050-Biotin)

Selected Variant

ARP38684_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

RNA binding motif protein 5

Gene Aliases

G15, H37, RMB5, LUCA15, LUCA-15

Gene ID

10181

Swiss Prot

P52756

Accession Number

NP_005769

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RBM5

Target

RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.

Partner Proteins

UBC; RNF2; SUZ12; WDR77; WBP11; LSM8; PRPF19; U2SURP; SNRNP200; U2AF2; PRPF8; ILF3; DHX15; LIG4; COPS5; SF3A2; SUMO2; GAPDH; BCL2L1; LRIF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RBM5 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 80%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Oh, J.J., (2008) Hum. Genet. 123 (1), 55-64

Shipping Conditions

Wet Ice

Protein Length

815

NCBI Gene Symbol

RBM5

NCBI GB Accession Number

RBM5

Host or Source

Rabbit

Protein Name

RNA-binding protein 5

Nucleotide Accession Number

NM_005778

Peptide Sequence

GSDKRVSRTERSGRYGSIIDRDDRDERESRSRRRDSDYKRSSDDRRGDRY

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog