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TAF1C Antibody - C-terminal region : Biotin (ARP38668_T100-Biotin)

Product Specifications

Gene Name

TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa

Gene Aliases

SL1, TAFI95, TAFI110, MGC:39976

Gene ID

9013

Swiss Prot

Q15572-2

Accession Number

NP_647610

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TAF1C

Target

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF.

Partner Proteins

UBC; Tbp; Taf1b; Taf1a; UFD1L; TTR; TK1; SMN1; H2AFX; TAF12; TAF1D; POLR1E; RRN3; TRIM24; TP53; UBTF; CD3EAP; MYC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

TAF1C is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

85kDa

References & Citations

Kimura, K., et al., (2006) Genome Res. 16 (1), 55-65

Shipping Conditions

Wet Ice

Protein Length

775

NCBI Gene Symbol

TAF1C

NCBI GB Accession Number

TAF1C

Host or Source

Rabbit

Protein Name

TATA box-binding protein-associated factor RNA polymerase I subunit C

Nucleotide Accession Number

NM_139353

Peptide Sequence

AKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPRMGF

Subunit

C

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