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SOX3 Antibody - C-terminal region : Biotin (ARP38649_T100-Biotin)

Product Specifications

Gene Name

SRY (sex determining region Y) -box 3

Gene Aliases

PHP, GHDX, MRGH, PHPX, SOXB

Gene ID

6658

Swiss Prot

P41225

Accession Number

NP_005625

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SOX3

Target

SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

Partner Proteins

TRRAP; SUMO1; SUMO2; PAX6

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

SOX3 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 77%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Savare, J., et al., (2005) Mol. Biol. Cell 16 (6), 2660-2669

Shipping Conditions

Wet Ice

Protein Length

446

NCBI Gene Symbol

SOX3

NCBI GB Accession Number

SOX3

Host or Source

Rabbit

Protein Name

Transcription factor SOX-3

Nucleotide Accession Number

NM_005634

Peptide Sequence

QRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQGAGTAVNG

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