SOX3 Antibody - N-terminal region : Biotin (ARP38648_T100-Biotin)
Product Specifications
Gene Name
SRY (sex determining region Y) -box 3
Gene Aliases
PHP, GHDX, MRGH, PHPX, SOXB
Gene ID
6658
Swiss Prot
P41225
Accession Number
NP_005625
Host
Rabbit
Reactivity
Human, Mouse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SOX3
Target
SOX3 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.
Partner Proteins
TRRAP; SUMO1; SUMO2; PAX6
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
SOX3 is supported by BioGPS gene expression data to be expressed in MCF7
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 85%; Pig: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
References & Citations
Savare, J., et al., (2005) Mol. Biol. Cell 16 (6), 2660-2669
Shipping Conditions
Wet Ice
Protein Length
446
NCBI Gene Symbol
SOX3
NCBI GB Accession Number
SOX3
Host or Source
Rabbit
Protein Name
Transcription factor SOX-3
Nucleotide Accession Number
NM_005634
Peptide Sequence
MRPVRENSSGARSPRVPADLARSILISLPFPPDSLAHRPPSSAPTESQGL
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