TP53BP2 Antibody - N-terminal region : FITC (ARP38619_P050-FITC)
Product Specifications
Gene Name
Tumor protein p53 binding protein, 2
Gene Aliases
BBP, 53BP2, ASPP2, P53BP2, PPP1R13A
Gene ID
7159
Swiss Prot
Q13625
Accession Number
NP_001026855
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TP53BP2
Target
TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. TP53BP2 contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. TP53BP2 is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family.
Partner Proteins
TXLNA; CWF19L2; SSX2IP; ATPAF2; ZGPAT; PLEKHN1; CCDC92; OTUB2; MTMR14; TBC1D22B; DCUN1D1; UBASH3A; PRPF31; NUTM1; HNRNPUL1; NXF1; BAIAP2; NDC80; TANK; TRAF4; LMO4; HIST1H2BC; TCL1A; ZNF26; SIAH1; PPP1CC; PPP1CB; POLR2L; GRB2; BCL2L1; BCL2; PRKAB2; UBC; AM
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
124kDa
References & Citations
Ju, H., et al., (2005) Int. J. Cancer 117 (6), 957-960
Shipping Conditions
Wet Ice
Protein Length
1127
NCBI Gene Symbol
TP53BP2
NCBI GB Accession Number
TP53BP2
Host or Source
Rabbit
Protein Name
Apoptosis-stimulating of p53 protein 2
Nucleotide Accession Number
NM_001031685
Peptide Sequence
TLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKL
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