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HCFC1 Antibody - N-terminal region : HRP (ARP38600_T100-HRP)

Selected Variant

ARP38600_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Host cell factor C1 (VP16-accessory protein)

Gene Aliases

CFF, HCF, HCF1, HFC1, MRX3, VCAF, HCF-1, PPP1R89

Gene ID

3054

Swiss Prot

P51610-3

Accession Number

AAH63435

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HCFC1

Target

HCFC1 is a member of the host cell factor family with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection.

Partner Proteins

FBXW11; BAP1; NUDCD3; CREB3; UBC; RPA3; RPA2; RPA1; EED; EEF1D; CREBZF; LMNA; OGT; POU2F1; NOTCH1; UL48; RBBP5; PPP1CB; PPP1CA; DPY30; WDR5; MAP3K7; HCFC1; EGFR; CLP1; YEATS2; CDK2; CUL3; USF1; NR2C1; THAP11; SIRT7; ELAVL1; SUMO2; ASH2L; SNRPN; SNRPB; YY1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

HCFC1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Director MGC Project, (2003) Direct Submission

Shipping Conditions

Wet Ice

Protein Length

428

NCBI Gene Symbol

HCFC1

NCBI GB Accession Number

HCFC1

Host or Source

Rabbit

Protein Name

Host cell factor 1

Nucleotide Accession Number

NM_005334

Peptide Sequence

GTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGH

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