HCFC1 Antibody - N-terminal region : Biotin (ARP38600_T100-Biotin)

Product Specifications

Gene Name

Host cell factor C1 (VP16-accessory protein)

Gene Aliases

CFF, HCF, HCF1, HFC1, MRX3, VCAF, HCF-1, PPP1R89

Gene ID

3054

Swiss Prot

P51610-3

Accession Number

AAH63435

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HCFC1

Target

HCFC1 is a member of the host cell factor family with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection.

Partner Proteins

FBXW11; BAP1; NUDCD3; CREB3; UBC; RPA3; RPA2; RPA1; EED; EEF1D; CREBZF; LMNA; OGT; POU2F1; NOTCH1; UL48; RBBP5; PPP1CB; PPP1CA; DPY30; WDR5; MAP3K7; HCFC1; EGFR; CLP1; YEATS2; CDK2; CUL3; USF1; NR2C1; THAP11; SIRT7; ELAVL1; SUMO2; ASH2L; SNRPN; SNRPB; YY1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Sample Type

HCFC1 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.