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EWSR1 Antibody - middle region : Biotin (ARP38594_P050-Biotin)

Product Specifications

Gene Name

Ewing sarcoma breakpoint region 1

Gene Aliases

EWS, EWS-FLI1, bK984G1.4

Gene ID

2130

Swiss Prot

Q01844

Accession Number

NP_005234

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human EWSR1

Target

EWSR1 is a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.This gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.

Partner Proteins

SSBP3; SEC24A; TFG; SEC24D; PEF1; MAPK1IP1L; ATPAF2; TRAF2; TRAF1; PLSCR1; PRR13; UBC; RPA3; RPA2; RPA1; EZH2; SUZ12; RNF2; BMI1; rev; ITCH; WBP4; PRMT1; CCDC7; YY1AP1; MRPS18B; UBD; CD81; RIOK2; NONO; ITGB5; ITGA4; FUS; FN1; EWSR1; EPAS1; EP300; HNRNPUL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

EWSR1 is strongly supported by BioGPS gene expression data to be expressed in HeLa, Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

References & Citations

Brandal, P., (2008) Genes Chromosomes Cancer 47 (7), 558-564

Shipping Conditions

Wet Ice

Protein Length

656

NCBI Gene Symbol

EWSR1

NCBI GB Accession Number

EWSR1

Host or Source

Rabbit

Protein Name

RNA-binding protein EWS

Nucleotide Accession Number

NM_005243

Peptide Sequence

RGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY

Frequently Asked Questions

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