CBFA2T3 Antibody - N-terminal region : HRP (ARP38578_T100-HRP)
Selected Variant
ARP38578_T100-HRP
Size: 100 µL
Product Specifications
Gene Name
Core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Gene Aliases
ETO2, MTG16, MTGR2, ZMYND4, RUNX1T3
Gene ID
863
Swiss Prot
O75107
Accession Number
BAA31276
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3
Target
The t (16;21) (q24; q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Partner Proteins
Zbtb38; Zbtb4; ZBTB33; GMEB2; SEC24A; MATN2; ZBTB47; UBC; RUNX1; TAL1; TRIM33; SIN3B; NCOR1; HDAC3; CBFA2T3; CBFA2T2; HDAC1; PRKAR2A; RUNX1T1; LDB1; TCF3; HDAC8; HDAC6; HDAC2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Sample Type
CBFA2T3 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
60kDa
Shipping Conditions
Wet Ice
Protein Length
545
NCBI Gene Symbol
CBFA2T3
NCBI GB Accession Number
CBFA2T3
Host or Source
Rabbit
Protein Name
Protein CBFA2T3
Nucleotide Accession Number
NM_005187
Peptide Sequence
MPASRLRDRAASSASGSTCGSMSQTHPVLESGLLASAGCSAPRGPRKGGP
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