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ATF1 Antibody - C-terminal region : Biotin (ARP38574_P050-Biotin)

Product Specifications

Gene Name

Activating transcription factor 1

Gene Aliases

TREB36, EWS-ATF1, FUS/ATF-1

Gene ID

466

Swiss Prot

P18846

Accession Number

NP_005162

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1

Target

ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.

Partner Proteins

UBC; SRA1; FOSL2; GABPB1; GABPA; EDF1; HNF1B; RPS6KA5; CAMK1; RPS6KA4; CAMK2G; PRKACA; CREBBP; SPI1; JUN; CREM; CREB1; ATF1; CSNK2A2; CSNK2A1; BRCA1; CSNK2B; CAMK2A; FOSL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 77%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

References & Citations

Iwasaki, K., (2007) J. Biol. Chem. 282 (31), 22335-22343

Shipping Conditions

Wet Ice

Protein Length

271

NCBI Gene Symbol

ATF1

NCBI GB Accession Number

ATF1

Host or Source

Rabbit

Protein Name

Cyclic AMP-dependent transcription factor ATF-1

Nucleotide Accession Number

NM_005171

Peptide Sequence

KNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV

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