NR1D2 Antibody - C-terminal region: Biotin (ARP38568_T100-Biotin)
Product Specifications
Gene Name
Nuclear receptor subfamily 1, group D, member 2
Gene Aliases
RVR, BD73, EAR-1R, REVERBB, REVERBbeta
Gene ID
9975
Swiss Prot
Q14995
Accession Number
NP_005117
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NR1D2
Target
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5'-AATGTAGGTCA-3' and 5'-ATAACTAGGTCA-3' and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Partner Proteins
MID2; RBPMS; TRIM27; NOTCH2NL; KRTAP10-9; KRT40; KRTAP4-2; PRMT6; SKP1; UBC; SIN3B; KAT5; NCOR1; TAF9; TAF6; HDAC1; GTF2B; NCOA5; UBE2I; CUL1; NR1D1; RGN
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
65kDa
Shipping Conditions
Wet Ice
Protein Length
579
NCBI Gene Symbol
NR1D2
Protein Name
Nuclear receptor subfamily 1 group D member 2
Nucleotide Accession Number
NM_005126
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
IRBAMLCAPN15AAP58120UL 120 µL
Rabbit Anti Human CAPN15 Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (Western Blot,IHC,ELISA) 120UL
Ask
View Details