MDS1 Antibody - N-terminal region: FITC (ARP38536_T100-FITC)
Product Specifications
Gene Name
Myelodysplasia syndrome 1
Gene Aliases
PRDM3, MDS1-EVI1
Gene ID
4197
Swiss Prot
Q13465
Accession Number
NP_004982
Host
Rabbit
Reactivity
Human, Mouse, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MDS1
Target
MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Human: 100%; Mouse: 93%; Zebrafish: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
19kDa
Shipping Conditions
Wet Ice
Protein Length
169
NCBI Gene Symbol
MDS1
Protein Name
MDS1 and EVI1 complex locus protein MDS1
Nucleotide Accession Number
NM_004991
Curated Selection
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